Contraindicated (1)pentobarbital will lower the extent or impact of cariprazine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is responsible for the formation and elimination of cariprazine's active metabolites.
pentobarbital will lessen the level or result of estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will reduce the extent or impact of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lower the extent or effect of terbinafine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the extent or effect of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
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pentobarbital will lessen the level or effect of cannabidiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Take into account an increase in cannabidiol dosage (based on scientific response and tolerability) when coadministered with a strong CYP3A4 inducer.
Observe Closely (1)pentobarbital will reduce the level or impact of hydrocodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Warning when discontinuing CYP3A4 inducers that are coadministered with hydrocodone; plasma concentrations of hydrocodone might maximize and can lead to probably deadly respiratory depressionSerious - Use Different (one)hydrocodone, pentobarbital.
pentobarbital will reduce the extent or result of eletriptan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will minimize the extent or effect of fostemsavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lower the level or outcome of darifenacin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the extent or outcome of amlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will get more info decrease the extent or result of pioglitazone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.
pentobarbital will decrease the level or result of fentanyl intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Coadministration of fentanyl with CYP3A4 inducers may lead to the minimize in fentanyl plasma concentrations, lack of efficacy or, maybe, enhancement of a withdrawal syndrome in the patient who may have produced physical dependence to fentanyl.